The rationale of perioperative intraperitoneal chemotherapy in the treatment of peritoneal surface malignancies

MH Katz, RM Barone - Surgical Oncology Clinics, 2003 - surgonc.theclinics.com
Peritoneal carcinomatosis, the infiltration of the visceral and parietal peritoneum with tumor,
most commonly represents an advanced form of intra-abdominal and pelvic malignancies
that is associated with a grim prognosis. Despite advances in its diagnosis since it was first
described in 1931 [1], the process has remained a therapeutic dilemma. Although survival
after diagnosis is related in large extent to the histopathology of the primary tumor, as a
group, patients with the disease have historically seen median survivals on the order of 3 …