Toll-like receptors and microbes take aim at each other

DM Underhill - Current opinion in immunology, 2004 - Elsevier
Current opinion in immunology, 2004Elsevier
Toll-like receptors (TLRs) are key components of effective innate immunity. As such,
pathogenic microorganisms must evade recognition by TLRs, manipulate the consequences
of TLR activation, or contend with the inflammatory consequences of TLR activation. Recent
studies have improved our understanding of the various mechanisms by which pathogenic
organisms manipulate the TLR recognition system.
Toll-like receptors (TLRs) are key components of effective innate immunity. As such, pathogenic microorganisms must evade recognition by TLRs, manipulate the consequences of TLR activation, or contend with the inflammatory consequences of TLR activation. Recent studies have improved our understanding of the various mechanisms by which pathogenic organisms manipulate the TLR recognition system.
Elsevier