Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and …
Y Yahata, Y Shirakata, S Tokumaru, K Yamasaki… - Journal of Biological …, 2003 - ASBMB
Vascular endothelial growth factor (VEGF) is a potent, multifunctional, endothelial-cell-
specific growth factor. It stimulates proliferation and migration of endothelial cells.
Characterization of intracellular signal transduction after VEGF and VEGF receptor (VEGFR)
interaction has demonstrated the involvement of the mitogen-activated protein kinase
pathway. However, several studies indicated that signal transducers and activators of
transcription (STAT) is another important pathway downstream of VEGF/VEGFR interaction …
specific growth factor. It stimulates proliferation and migration of endothelial cells.
Characterization of intracellular signal transduction after VEGF and VEGF receptor (VEGFR)
interaction has demonstrated the involvement of the mitogen-activated protein kinase
pathway. However, several studies indicated that signal transducers and activators of
transcription (STAT) is another important pathway downstream of VEGF/VEGFR interaction …
