Glaucomatous vision loss results from the progressive degeneration of optic nerve axons
and the death of retinal ganglion cells. This process is accompanied by dramatic alterations
in the functional properties and distribution of glial cells in both the retina and the optic nerve
head in a reaction commonly referred to as glial activation. The recent availability of rodent
and cell culture glaucoma models has substantially contributed to our knowledge of glial
activation under glaucomatous conditions. Conclusions drawn from these studies have led …