[HTML][HTML] AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
YQ Chen, MS Kuo, S Li, HH Bui, DA Peake… - Journal of Biological …, 2008 - ASBMB
AGPAT6 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) family
that appears to be important in triglyceride biosynthesis in several tissues, but the precise
biochemical function of the enzyme is unknown. In the current study, we show that AGPAT6
is a microsomal glycerol-3-phosphate acyltransferase (GPAT). Membranes from HEK293
cells overexpressing human AGPAT6 had higher levels of GPAT activity. Substrate
specificity studies suggested that AGPAT6 was active against both saturated and …
that appears to be important in triglyceride biosynthesis in several tissues, but the precise
biochemical function of the enzyme is unknown. In the current study, we show that AGPAT6
is a microsomal glycerol-3-phosphate acyltransferase (GPAT). Membranes from HEK293
cells overexpressing human AGPAT6 had higher levels of GPAT activity. Substrate
specificity studies suggested that AGPAT6 was active against both saturated and …