Odds of testing positive for SARS-CoV-2 following receipt of 3 vs 2 doses of the BNT162b2 mRNA vaccine

T Patalon, S Gazit, VE Pitzer, O Prunas… - JAMA Internal …, 2022 - jamanetwork.com
Importance With the evidence of waning immunity of the mRNA vaccine BNT162b2 (Pfizer-
BioNTech), a nationwide third-dose (booster) vaccination campaign was initiated in Israel
during August 2021; other countries have begun to administer a booster shot as well.
Objective To evaluate the initial short-term additional benefit of a 3-dose vs a 2-dose
regimen against infection of SARS-CoV-2. Design, Setting, and Participants This preliminary
retrospective case-control study used 2 complementary approaches: a test-negative design …