Longitudinal study of cognitive and cerebral metabolic changes in Parkinson's disease
T Baba, Y Hosokai, Y Nishio, A Kikuchi… - Journal of the …, 2017 - Elsevier
Objective To investigate the cortical metabolic alterations that precedes longitudinal
cognitive decline in Parkinson's disease (PD). Methods We analyzed the data of 46 PD
patients who did not have dementia at baseline and completed 3-year follow-up. Based on
the results of general cognitive, memory and visuospatial tests, patients were classified into
cognitively normal PD (PD-CogNL), PD with mild cognitive impairment (PD-MCI), and PD
dementia (PDD). The regional cerebral glucose metabolism at rest was measured using 18 …
cognitive decline in Parkinson's disease (PD). Methods We analyzed the data of 46 PD
patients who did not have dementia at baseline and completed 3-year follow-up. Based on
the results of general cognitive, memory and visuospatial tests, patients were classified into
cognitively normal PD (PD-CogNL), PD with mild cognitive impairment (PD-MCI), and PD
dementia (PDD). The regional cerebral glucose metabolism at rest was measured using 18 …
