Frequency of cholinergic and caudate nucleus dopaminergic deficits across the predemented cognitive spectrum of Parkinson disease and evidence of interaction …
Importance Little is known about the relative contributions of multisystem degenerative
processes across the spectrum of predemented cognitive decline in Parkinson disease (PD).
Objective To investigate the relative frequency of caudate nucleus dopaminergic and
forebrain cholinergic deficits across a spectrum of cognitively impaired patients with PD to
explore their relative, individual, and combined contributions to cognitive impairment in PD.
Design, Setting, and Participants A cross-sectional study at an academic movement …
processes across the spectrum of predemented cognitive decline in Parkinson disease (PD).
Objective To investigate the relative frequency of caudate nucleus dopaminergic and
forebrain cholinergic deficits across a spectrum of cognitively impaired patients with PD to
explore their relative, individual, and combined contributions to cognitive impairment in PD.
Design, Setting, and Participants A cross-sectional study at an academic movement …