[CITATION][C] Role of abnormal free fatty acid metabolism in the development of non-insulin-dependent diabetes mellitus

GM Reaven, YDI Chen - The American journal of medicine, 1988 - Elsevier
T he goal of this presentation is to formulate a hy-pothesis to account for the development of
fasting hyperglycemia in patients with non-insulin-dependent diabetes mellitus (NIDDM).
Although it is quite clear that defects in both insulin secretion and insulin action exist in
patients with NIDDM, controversy continues to exist as to the role that these metabolic
abnormalities play in the development of NIDDM [l]. Indeed, at the present time it is not
possible to present a unitarian hypothesis that would please all those working in this …