Endocrine and metabolic adaptation to obesity and starvation

EAH SIMS, ES HORTON - The American journal of clinical nutrition, 1968 - Elsevier
Several of the endocrine and metabolic changes that occur in spontaneous obesity have
been reviewed and compared to the findings in a study of experimental obesity in man in
progress at the University of Vermont and the Vermont State Prison. With few exceptions, the
production of a 15–30% gain in weight by increased calorie intake in lean volunteers
resulted in endocrine-metabolic changes similar to those observed in spontaneous obesity,
as illustrated diagrammatically in Table I. This suggests that many of these changes may be …