Improvement of Cutaneous Hereditary Hemorrhagic Telangiectasia With Pazopanib—A Multikinase Inhibitor

JY Moon, EM Ajebo, JR Gossage… - JAMA …, 2022 - jamanetwork.com
Discussion This case study reports the observation of improvement of cutaneous HHT
lesions using treatment with pazopanib. Cutaneous HHT, in addition to being visually
bothersome to patients, is frequently associated with bleeding. Current traditional
treatments, such as laser treatment, can provide relief but are limited, as they do not
prophylactically prevent recurrence. 3, 4 Following continuous therapy with pazopanib for
more than 3 years, he was noted to have a substantial reduction in the size and number of …